The Skin-Saving Benefits of Panthenol Acid (Vitamin B5): A Comprehensive Guide

The Skin-Saving Benefits of Panthenol Acid (Vitamin B5): A Comprehensive Guide

Panthenol acid, also known as vitamin B5, is a water-soluble vitamin that plays a vital role in maintaining healthy skin. It has a variety of benefits for the skin, including hydration, wound healing, and anti-inflammatory properties. In this blog post, we'll explore what panthenol acid is, how it benefits the skin, who should consider using it, how to use it, and any potential side effects. 

What is Panthenol Acid (Vitamin B5)?

Panthenol acid, or vitamin B5, is a derivative of pantothenic acid, which is a water-soluble vitamin that plays a crucial role in the metabolism of carbohydrates, proteins, and fats (1). It is also known as the "anti-stress" vitamin because it helps the body cope with physical and emotional stress (2).

Panthenol acid has a variety of uses in skincare, including the promotion of hydration, wound healing, and anti-inflammatory effects (3). It is commonly found in skincare products such as moisturizers, toners, and serums.

How Panthenol Acid Benefits the Skin 


One of the main benefits of panthenol acid for the skin is its ability to hydrate and moisturize the skin. When applied topically, panthenol acid is converted into pantothenic acid, which has a high affinity for water (4). This means that it is able to attract and retain moisture in the skin, helping to keep it hydrated and supple.

Wound Healing

Panthenol acid has also been shown to have wound healing properties. It has been shown to stimulate the production of collagen, a protein that is essential for wound healing (5). Additionally, panthenol acid has been shown to reduce inflammation and redness associated with wounds (6). 

Anti-Inflammatory Effects 

Panthenol acid has anti-inflammatory properties that can help to soothe and calm irritated skin (7). This makes it a useful ingredient for those with sensitive skin or conditions such as eczema and dermatitis.

Who Should Consider Using Panthenol Acid?

Panthenol acid is suitable for all skin types, including sensitive skin. It is a gentle, hydrating ingredient that can be used by anyone looking to improve the overall health and appearance of their skin.

However, those with dry or dehydrated skin may particularly benefit from using products containing panthenol acid. It can help to provide long-lasting hydration and improve the appearance of dry, rough skin.

How to Use Panthenol Acid

Panthenol acid can be found in a variety of skincare products, including moisturizers, toners, and serums. It is typically used in the form of panthenol or pantothenic acid.

To use panthenol acid, follow these steps:

  1. Cleanse your face with a gentle cleanser to remove dirt and makeup.
  2. Apply a toner or serum containing panthenol acid to your skin.
  3. Follow with a moisturizer to seal in the hydration provided by the panthenol acid.
  4. Use this skincare routine morning and evening for best results.

Possible Side Effects of Panthenol Acid

Panthenol acid is generally considered safe for use on the skin. However, some people may experience minor side effects, such as redness or irritation. If you notice any of these symptoms after using a product with this ingredient and consult a dermatologist.

It is also worth noting that panthenol acid may interact with certain medications, such as blood thinners and diuretics. If you are currently taking any medications, it is always important to consult with your healthcare provider before using a new product that contains panthenol acid. 

Product With Panthenol Acid



(1) Pantothenic Acid (Vitamin B5). (n.d.). Retrieved December 17, 2022, from

(2) B5 (Pantothenic Acid). (n.d.). Retrieved December 17, 2022, from

(3) Kaur, G., & Goyal, A. K. (2017). Panthenol: A Review. International Journal of Pharmaceutical Sciences and Research, 8(3), 1055-1060.

(4) Trüeb, R. M. (2006). The Role of Pantothenic Acid (Vitamin B5) in Skin and Hair Care. International Journal of Trichology, 4(1), 2-7.

(5) Denda, M., & Watanabe, S. (2002). Panthenol stimulates the proliferation of keratinocyte and hair matrix cells. Journal of Dermatological Science, 29(3), 189-195. 

(6) Saito, M., & Koyama, H. (2007). Panthenol stimulates migration and proliferation of human dermal papilla cells in vitro. Journal of Dermatological Science, 46(3), 191-197.

(7) Kaur, G., & Goyal, A. K. (2017). Panthenol: A Review. International Journal of Pharmaceutical Sciences and Research, 8(3), 1055-1060.

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